Saturday, July 28, 2012

A Short Lesson on True Estate | Preschoolers home schooling

Jul 28

Posted by DehoffFaherty on Saturday Jul 28, 2012 Under Uncategorized

Exactly where did the notion that males ought to acquire homes for females come from? Many people say that this really is depending on our natural instinct. Like any other animal, parents need to safeguard their young for the continuation from the species. Anyway, asked that query because I wanted to know why business relating to real estate is all of a sudden producing becoming common. Just before you had the acquiring and promoting of properties. Now, with the widespread use of the Internet, we have actual estate trading which can be fundamentally I purchase yours you buy mine kind of arrangement.
The term genuine estate is utilised to refer to any property, that is permanently attached to land for example buildings and homes. Most people refer to it as true house but there are scenarios wherein the term actual estate is used for the land along with the building with each other even though genuine house refers to the ownership rights of the land itself. However, the word genuine is utilised to categorize these properties as things as opposed to folks. Records show that the concept of genuine estate could be traced as far back as 1666.
With the concept of private home becoming a lot more widespread, real estate has become a significant location of business within the Usa. The truth is, economists claim that the purpose for the recent economic slump is because of the lower revenue generated by this market. In order for the US to have back on track, Americans need to view land and buildings as an investment.
There are lots of varieties of real estate: residential, commercial or industrial property. Probably the most typical transactions involve the getting and selling of residential properties including apartments, condominiums and a duplex. Often households who wish to move to a various state finds it hard to find dwellings on their own so they typically do a map search in the region they?re moving to so as to locate any houses which are either for sale or for rent. This way, they get to choose the properties they want without having obtaining to travel however, thereby saving time, work and cash. In some situations, individuals speak to a genuine estate agent who can then give them a tour from the region in order that they get to determine the homes and to possibly bargain for the price tag in the house.
In US and Canada, obtaining property is easy due to the existence with the a number of listing program or MLS a data base wherein genuine estate brokers can share details in regards to the properties their customers are organizing to sell, or in some cases, planning to get. A lot of people who need to acquire a home typically have no concept where to begin so they contact a genuine estate broker. Whenever you do so, the broker searches the MLS to locate specifics regarding the home. At present, you can find about 800 various MLS in the US with new competitors like Google Base, Craigslist and Cribfinder getting into the public domain.

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Source: http://www.toyspreschool.org/uncategorized/a-short-lesson-on-true-estate/

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Study finds novel therapy that may prevent damage to the retina in diabetic eye diseases

Study finds novel therapy that may prevent damage to the retina in diabetic eye diseases [ Back to EurekAlert! ] Public release date: 27-Jul-2012
[ | E-mail | Share Share ]

Contact: Barbara Sefton
bwsefton@umich.edu
734-763-6967
University of Michigan Health System

Targeting a key protein blocks two important pathways related to blood vessel leakage in diabetic retinopathy

Researchers at the University of Michigan Kellogg Eye Center have identified a compound that could interrupt the chain of events that cause damage to the retina in diabetic retinopathy. The finding is significant because it could lead to a novel therapy that targets two mechanisms at the root of the disease: inflammation and the weakening of the blood barrier that protects the retina.

To date, treatments for diabetic retinopathy, the leading cause of blindness among working-age Americans, have been aimed largely at one of those mechanisms.

In diabetic retinopathy, damage to the retina results, in part, from the activity of vascular endothelial growth factor (VEGF), a protein that weakens the protective blood-retinal barrier. Recent drugs targeting VEGF have exhibited good response for nearly half of the patients with diabetic retinopathy. But researchers believe that there is also an inflammatory component that may contribute to the disease process.

The study, published in the Biochemical Journal, June 2012 [epub ahead of print] identifies a specific protein common to both pathways as an important target in regulating the disease process in which blood vessels become leaky, and provides a drug that may be developed into a therapeutic intervention for patients in which anti-VEGF treatment alone is not sufficient.

"In diabetic retinopathy and a host of other retinal diseases, increases in VEGF and inflammatory factors some of the same factors that contribute to the response to an infection cause blood vessels in the eye to leak which, in turn, results in a buildup of fluid in the neural tissue of the retina," says David A. Antonetti, Ph.D., Professor, Department of Ophthalmology and Visual Sciences and Molecular and Integrative Physiology, who has also been awarded a Jules and Doris Stein Professorship from Research to Prevent Blindness. "This insidious form of modified inflammation can eventually lead to blindness."

The compound targets atypical protein kinase C (aPKC), required for VEGF to make blood vessels leak. Moreover, Antonetti's laboratory has demonstrated that the compound is effective at blocking damage from tumor necrosis factor also elevated in diabetic retinopathy that comprises part of the inflammation. Benefits of this compound could extend to therapies for uveitis, or changes to the brain blood vessels in the presence of brain tumors or stroke.

"This is a great leap forward," says Antonetti. "We've identified an important target in regulating blood vessel leakage in the eye and we have a therapy that works in animal models. Our research is in the early stages of development. We still have a long way to go to demonstrate effectiveness of this compound in humans to create a new therapy but the results are very promising."

###

Novel Atypical PKC Inhibitors Prevent Vascular Endothelial Growth Factor-Induced Blood-Retinal Barrier Dysfunction, 22 June 2012 [epub ahead of print]

Funding sources: National Institutes of Health; Juvenile Diabetes Research Foundation; The Jules and Doris Stein Professorship from Research to Prevent Blindness; Fight for Sight Research Foundation


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Study finds novel therapy that may prevent damage to the retina in diabetic eye diseases [ Back to EurekAlert! ] Public release date: 27-Jul-2012
[ | E-mail | Share Share ]

Contact: Barbara Sefton
bwsefton@umich.edu
734-763-6967
University of Michigan Health System

Targeting a key protein blocks two important pathways related to blood vessel leakage in diabetic retinopathy

Researchers at the University of Michigan Kellogg Eye Center have identified a compound that could interrupt the chain of events that cause damage to the retina in diabetic retinopathy. The finding is significant because it could lead to a novel therapy that targets two mechanisms at the root of the disease: inflammation and the weakening of the blood barrier that protects the retina.

To date, treatments for diabetic retinopathy, the leading cause of blindness among working-age Americans, have been aimed largely at one of those mechanisms.

In diabetic retinopathy, damage to the retina results, in part, from the activity of vascular endothelial growth factor (VEGF), a protein that weakens the protective blood-retinal barrier. Recent drugs targeting VEGF have exhibited good response for nearly half of the patients with diabetic retinopathy. But researchers believe that there is also an inflammatory component that may contribute to the disease process.

The study, published in the Biochemical Journal, June 2012 [epub ahead of print] identifies a specific protein common to both pathways as an important target in regulating the disease process in which blood vessels become leaky, and provides a drug that may be developed into a therapeutic intervention for patients in which anti-VEGF treatment alone is not sufficient.

"In diabetic retinopathy and a host of other retinal diseases, increases in VEGF and inflammatory factors some of the same factors that contribute to the response to an infection cause blood vessels in the eye to leak which, in turn, results in a buildup of fluid in the neural tissue of the retina," says David A. Antonetti, Ph.D., Professor, Department of Ophthalmology and Visual Sciences and Molecular and Integrative Physiology, who has also been awarded a Jules and Doris Stein Professorship from Research to Prevent Blindness. "This insidious form of modified inflammation can eventually lead to blindness."

The compound targets atypical protein kinase C (aPKC), required for VEGF to make blood vessels leak. Moreover, Antonetti's laboratory has demonstrated that the compound is effective at blocking damage from tumor necrosis factor also elevated in diabetic retinopathy that comprises part of the inflammation. Benefits of this compound could extend to therapies for uveitis, or changes to the brain blood vessels in the presence of brain tumors or stroke.

"This is a great leap forward," says Antonetti. "We've identified an important target in regulating blood vessel leakage in the eye and we have a therapy that works in animal models. Our research is in the early stages of development. We still have a long way to go to demonstrate effectiveness of this compound in humans to create a new therapy but the results are very promising."

###

Novel Atypical PKC Inhibitors Prevent Vascular Endothelial Growth Factor-Induced Blood-Retinal Barrier Dysfunction, 22 June 2012 [epub ahead of print]

Funding sources: National Institutes of Health; Juvenile Diabetes Research Foundation; The Jules and Doris Stein Professorship from Research to Prevent Blindness; Fight for Sight Research Foundation


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2012-07/uomh-sfn072712.php

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Friday, July 27, 2012

Fred Willard Jokes About His Arrest For Lewd Conduct (VIDEO)

Fred Willard Jokes About His Arrest For Lewd Conduct (VIDEO)

Fred Willard, the 72-year-old actor arrested for lewd behavior at the Tiki Theater in Hollywood, is laughing off the embarrassing situation. The funnyman who is [...]

Fred Willard Jokes About His Arrest For Lewd Conduct (VIDEO) Stupid Celebrities Gossip Stupid Celebrities Gossip News

Source: http://stupidcelebrities.net/2012/07/fred-willard-jokes-about-his-arrest-for-lewd-conduct-video/

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Health Care's New Rules: If You Don't Buy Insurance, Will You ...

Now that the Supreme Court has decided that ObamaCare?s mandate to buy health insurance is a tax, will the IRS be able to collect it?

Generally speaking, if you owe the IRS, it will get the money from you?with the possible exception of the ObamaCare tax. Though ObamaCare?s individual mandate imposes a tax on people who do not purchase government-approved health insurance, the law explicitly neuters the IRS?s ability to collect the tax.

Bizarre? Yes. And it matters. If policymakers expect uninsured young people to buy health insurance when it is even more expensive than it is today, the threat of serious consequences for not doing so must be real. Yes, the threat that the IRS might come after you if you do not do what you are told looks real at first glance. But Democratic politicians, fearing public backlash for making the mandate too intrusive, pulled its teeth.

First, the tax (nee penalty) is too small to matter to the people who are its target. In 2014, the tax will be the larger of $95 or 1 percent of taxable income for an individual. By 2016 it rises to $695 or 2.5 percent of income. Young people would not want to pay a dollar if they could avoid it, but avoiding the tax means signing up for insurance that many do not think they need. That insurance is not free. Even with subsidies, they will pay at least 3 percent of their incomes for premiums and up to 6 percent of the cost of the insurance in deductibles and copayments. That adds up to a lot more than 95 bucks.

Second, the law counts on most of the scofflaws turning themselves in. If you do not have insurance and think you owe the tax, then you will be asked to check a box to that effect on your tax return. If you choose to ignore the mandate, you might also choose not to check the box. But even those who do confess that they do not have insurance may not be liable for the new tax. Illegal aliens, Native Americans, prisoners, those who are without insurance for less than 3 months, those who do not have to file an income tax return, anyone who faces a hardship or cannot find affordable coverage, and others are all exempt.

Third, the law requires the IRS to sift through 140 million income tax returns to track down the few scofflaws who are actually liable. This requires collecting information from both the insurance companies and the individual filers in an expensive feat of bureaucratic detective work. What are the specifics? The details of any plan other than taking your word for it have not been worked out yet, but the likely scenario finds insurance companies sending documentation to the IRS and to the taxpayer, which the taxpayer would then include with his return. That means even more bureaucracy and regulatory burden than the healthcare industry and the IRS currently have. And more bureaucracy and regulation mean greater expense, both to insurers (who will pass those costs to consumers in higher premiums) and to the government.

Taking all parts of ObamaCare together, the IRS is expected to spend $881 million from 2010 through 2013 on thousands of new workers and upgrades to computer systems?amazing, since the bulk of ObamaCare does not even go into effect until later years.

Finally, even if the IRS has determined that you owe the new tax, it has very limited ability to force you to pay it. Basically, the IRS has two options: To ask you for the money and to reduce the size of your tax refund. But the IRS cannot reduce your refund unless you overpay. Since taxpayers have great control over their withholding, a savvy taxpayer who does not want to buy insurance could easily work the system to ensure that the IRS could not hold back his refund to enforce the mandate tax. And half of American households do not owe any income tax to begin with, so good luck getting the money from them. In addition, with electronic filing, the IRS may have already sent you the full refund before they?ve figured out that you owe the ObamaCare tax. All in all, it could take years for the IRS to collect its money.

This contrasts sharply with the way the IRS collects other taxes. To put it simply, the IRS gets the money it is owed because it has broad powers to enforce compliance. After all, there?s a reason we?re all scared of the IRS.

To enforce tax compliance, the government can bring a lawsuit against you, but that option is generally reserved for the most serious tax evaders?not individuals who owe a $695 penalty. In contrast, the ObamaCare law says that anyone who does not have health insurance and fails to pay the tax cannot be criminally prosecuted or criminally penalized. There goes the government?s strongest weapon.

What happens most of the time is very simple: If you refuse to pay your taxes, then the government takes your stuff. The government can take all the assets you currently have and assets you expect to receive in the future. For example, the money you have in your checking and savings accounts, your car, your boat, your retirement account, any rental income, and wages that have not been paid to you can be taken by the IRS in order to collect the money you owe. The IRS?s power is so strong that it holds third parties liable if they choose not to surrender property that the IRS demands. So your bank has to comply with the IRS.

Not so if the tax you refuse to pay is the ObamaCare tax. Under ObamaCare, the IRS cannot seize any of your property to enforce the mandate penalty. The IRS cannot go after the money in your bank accounts, and it can?t sell your car. It can?t send you to jail, and it can?t touch your stuff.

Congress has enacted a law that cannot be enforced. Congress purposely limited the enforcement powers of the IRS to avoid the public outcry that a strong mandate to buy government-approved insurance would evoke. The mandate may be constitutional, but as Chief Justice Roberts pointed out, a constitutional law is not automatically good policy.

The government?s inability to enforce the individual mandate is just one of many problems with ObamaCare. Mandate or not, laws should be enforceable, and they should be reasonable. This law has to go. The American public should turn the tables on the government and enforce a mandate of its own: Create and execute reasonable health policy.

Joseph Antos is the Wilson H. Taylor Scholar in Healthcare and Retirement Policy at the American Enterprise Institute, where Michael R. Strain is a research fellow. This post first appeared at The American.

Source: http://thehealthcareblog.com/blog/2012/07/27/health-cares-new-rules-if-you-dont-buy-insurance-will-you-really-pay-the-tax/

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Malaysian giant MOL enters Australia's online gaming space with ...

The real-action, online gaming is the fastest-growing segment of the market. In fact, by 2014, online games will itself be a billion-dollar market, according to PricewaterhouseCoopers? projection.

So, it?s not a huge surprise to see some M&A action in this space as companies jostle for market share.

Recently, Ocash, the Australian startup, acquired OnlineGamez Australia, a distributor of online game credits in Australia and New Zealand. This week,?Malaysian Internet payments giant MOL Global announced the acquisition of a majority stake in Ocash itself.

?This is a significant step for MOL to continue to build and strengthen its business strategy across the Asia Pacific region,? said Craig White, president of MOL Global.

White said the partnership would ?provide more business opportunities for our region?s game developers and publishers as they will be able to extend their reach via MOL to consumers outside the Asian region.?

MOL is one of the largest online payment providers in the world. It has more than 600,000 physical and online payment channels, besides partnerships with over 150 online game publishers and social networks worldwide including Facebook, Zynga and Electronic Arts.

Ocash founder Budi Handoko has been named the chief executive of MOL Australia, and will power the company?s growth Down Under.

?We identify ourselves in line with the vision of MOL and the synergy between both organisations will allow our businesses to reach new heights,? said Handoko, an online game specialist. ?At the same time, our growing player community will be able to gain new secured channels to purchase various popular digital products such as Facebook Credits, as well as be introduced to MOL?s huge portal of international and Asian games.?

Ocash has specialised in processing payments for online games credits in the Australia and New Zealand markets. Its flagship product ? ocash points ? is a virtual credit utilised by online game enthusiasts to purchase popular game credits from various game publishers.

PricewaterhouseCoopers predicts consumer spending on games in Australia will increase to $1,584 million in 2014, mainly on the strength of growth in online games and wireless games. Estimated compound annual growth in consumer spending for online games (13.6%) and wireless games (13%) for 2010-2014 is significantly higher than that for consoles and handheld devices (5.8%).

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Source: http://anthillonline.com/online-gaming-gets-a-boost-ocash-beckons-mol-to-australia/

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Thursday, July 26, 2012

London Eater ? London food blog and restaurant reviews and ...

For my birthday this year, I was looking to drink something a little special and so BBR became an obvious choice for it carries a list of classy old world wine labels, but with modest mark-ups. Prices on the wines track closely to the market conditions, generally with 20 to 30% margin over retail and do present tremendous value compared to ?finer? establishments. Let?s see there the now luxury brand right bank star, Cheval Blanc, the 1996 for ?500; Conseillante, a consistent Pomerol estate (Merlot!) , from a generally positive vintage, 1990 for ?526; ?98 La Mouline, the most feminine of the trio of ?Lalas? from Northern Rhone producer Guigal for ?432. There?s even a Unico by Vega Sicilia, what is regarded as Spain?s version of a first growth, the 1999 for ?317.

1985 Ch Haut Brion, Graves. ?392.

It was an easy decision to pick this claret. It?s got a quarter century of bottle age, and a glut of cellartracker reviews indicating that it is in a really nice place at the moment. In another restaurant, a first growth Bordeaux would easily command a four digit price, so ?392 + 12.5% is a ?relative bargain?. It was also surprisingly close to cost price (330/btl in bond) so it seemed er, sensible to take a punt. So to secure it (by the time you read this, the wine list might have been reviewed), I had paid for the wine upfront sometime in April, 12 weeks ahead of this meal.

Of all the Bordelais, I am most familiar with wines from the Graves region. While the mighty Pauillacs boast fruit and power, I believe the most intriguing clarets are from this region. The name is a direct reference to the soil character and it is the gravel and clay which are said to give rise to the trademark aromas of smoke and cigars, or broadly speaking the sense of place these wines are so famous for.

I?ve sampled small sips of ?78 Haut Brion (fucking wow), ?66 La Mission (fading in 2012 it seems), the lauded 09 Smith Haut Laffite (TANNINS) but my favourites are the fleshy Chevalier reds (I haven?t tried their whites) which are decent expressions of the region and relatively affordable at ?50 a pop. I have a case of the 09s cellared which I plan to break out when I retire.

I think there is no better way to experience the best of Graves than a good bottle from the Chieftain of Pessac that is Haut Brion (ok maybe its sister estate La Mission Haut Brion). It?s very noble stuff. The Domaine would probably tell you how it has been famously revered through its long history, it even found its way to King Charles II?s dinner table. In those days, it defined a new breed of claret while today it is reputed as the oldest and the only First Growth outside of the Medoc, per the dated left bank 1855 classifications.

Considering its age, the bottle was in a healthy state, at mid-neck fill levels. Though it was slightly worrying to see a perfectly legible label, suggesting a mostly dry shelf-life, which may make for dry corks, but that?s just speculating by inspection. The sommelier popped and poured a small sample in my glass and decanted the rest. He left maybe about a shot?s worth in the bottle, as there was quite a bit of expected sediment. The cork looked pristine, stained to about halfway up, indicating the wine had crucially taken in some air in its long life.

Even before swirling, savoury secondary aromas of tar, ash, cigar, leather and maybe smoked ham were present. It instantly reminded me of the ?78. So all fears subsided ? the bottle had been carefully stored through its lifetime.

As the wine breathed, the fruit started to unfurl, plums or maybe even figs ? a flash of its youth. Through the night, the wine became less shy, more perfumed and more floral. It was a tremendous pleasure to smell the wine and I spent more time doing that than drinking. Obviously I don?t drink trophy wines regularly ? if at all ? so there might be more aromas which I couldn?t detect. However it definitely felt like a step change to anything I?d drank in recent memory.

On the palate, it was simply the smoothest wine I?d ever tasted. This really was liquid silk, as abused as the term may be. It felt polished and precise. This mature claret seemed almost Rhone-like in weight with all the tannins now fallen away. Spicy, maybe soya sauce, but with black fruit in the background and some sweetness too ?somewhere in the mix.

The wine changed perceptibly in the glass as we drank it over four hours. It was fruitier to start and grew to a spicier and more savoury monster toward the end. All the while however, it maintained a poise, an ultra-smooth, lithe mouth feel and drank beautifully till the very last drop. I remembered the long sizzling finish and counted 15, maybe 30 seconds, lingering fruitiness?

?wow. So this is First growth quality.

We were still conscious that this was just fermented grape juice, but it was surprising how harmonious the wine was. There weren?t any rough edges, it was so smooth, so balanced and such a delight to drink.

Was it worth ?440? Is any liquid ? at least 80% water ? kept in a glass bottle for a long time worth that kind of money? It probably retailed closer to ?44 when it was bottled in ?88. So maybe not, but I suppose what you pay for is the promise of intangibles involving emotion and pleasure. Though we did entertain the idea of trying to quantifying this ?greatness? and subjectively, it felt like this wine could justifiable be worth ?300+. ?200 would be good value (in relative terms) , but if it were available for say ?100, we would probably buy a case of it.

Nevertheless, the 1985 is certainly in a nice place today, I felt we drank a great bottle of a great wine providing for a truly memorable experience and this was absolutely worth it.

And now to the food..

Six Colchester Grade ?A? Rock Oysters, ?13.25.

We started with healthy looking rock oysters from Colchester. Creamy, crisp but not as thrilling as the Dorset rocks which our fishmonger sell at our farmers market at Queen?s Park.

Venison Tartare Imperial, with 15g Sturgeon Caviar, ?29.75

I wasn?t expecting the caviar to be anything more than just an extravagant splurge, but the deep saltiness, sticky texture did appear to enrich the tartare. A little excessive but it was an enjoyable one-off.

Crab Salad with Chilli Avocado Mayo, ?11.50

Generously loaded with freshly picked crab, needed a lot of lemon juice but generally pleasing.

Crispy, Pressed and Roaster Belly of Suckling Pork, with Truffle Gravy, ?21.25

This was hugely enjoyable, the crackling was just smashing, the pork was delicious. The black pudding was a little sweet, lighted scented with truffle gravy. Yummy, but probably more so in winter.

Veal FIllet Holstein, with Quail Egg, Anchovies, Bacon and Truffle Gravy, ?21.75
with Lobster Mash, ?6.75.

I?ve had this dish on a couple of separate occasions and have always been impressed. It?s just so dependable, so classic. Served pink, also with lashings of truffle gravy, it was comforting, a joy to eat and it complimented the wine well enough.

Although the lobster mash was certainly the best thing we ate. It was like mash soaked in a lobster bisque. Flavours of fluidised shell, and with generous claw meat mixed in. It was a course unto itself. To me, it seemed exactly what you?d expect lobster mash to taste like. It?s miles ahead of the Goodman version.

Chocolate Glory, MK II. ?9.75.

With chocolate jivara mousse, brownie, meringue and passionfruit orange jelly in a golden shell that disintegrates as hot chocolate sauce is poured over it.

So we paid ?440 for wine, ?139 for the food plus service, totaling ?579. In the end, it was a memorable meal. This old-fashioned-ish brasserie with an eccentric approach to hospitality was a success for a private celebration. Nothing but love for the plush leather-seated booths.

Details

Bob Bob Ricard
Anglo-Russian All Day Diner ?50pp
1 Upper James Street, London, W1F 9DF
Tel: +44 (0)203 145 1000
Tube: Piccadilly Circus

Bob Bob Ricard on Urbanspoon

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Tags: Bob Bob Ricard, british, london, restaurant, soho

Source: http://londoneater.com/2012/07/25/bob-bob-ricard-2012/

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Fed has few options as global growth slows

By John W. Schoen, Senior Producer

For the first time in decades, the U.S. Federal Reserve is looking like a toothless tiger.

As it becomes clearer that the multiple gears of the worldwide economy are slowing in unison, pressure is mounting on the world's largest central bank to spur growth.?But with the cost of borrowing money already at historic lows, it?s far from clear whether further measures aimed at making money cheaper will help.

"They have a hammer and they're looking for a nail," Alan De Rose, managing director of government trading and finance at Oppenheimer, told Reuters.

The Fed's policy-setting committee meets next week amid reports that it may be close to taking fresh action to stimulate the flagging economy.

With businesses worried about taking on new risk and households struggling to make ends meet, fresh data this week point to an ongoing economic slowdown in the U.S.

The Commerce Department?s initial estimate of second quarter gross domestic product, due Friday, is expected to show the growth rate slowed to 1.2 percent from 1.9 percent in the first three months of the year. The slowdown follows a series of monthly reports pointing to a weakening job market and a stubbornly high unemployment rate.

American businesses continue to feel the impact of a deepening recession in Europe. Surveys of Europe's private sector this week showed?the contraction that began in the eurozone's weaker economies has now spread to Germany and France. Across the 17 countries that use the euro, manufacturing output has tanked. Consumers are gloomier than they've been since 2009.

As the European meltdown weighs on the overall U.S. economy, states that rely heavily on exports are most at risk from the deepening crisis overseas.

When the global credit markets collapsed in the fall of 2008, central banks around the world quickly exhausted the primary tool they?ve reliably used to fight financial fires for decades: slashing the interest rates on money lent directly to banks. Despite those efforts, the world economy slid into a nasty recession.

Since then, the Fed has employed a set of new tools, including the purchase of some $2 trillion in bonds to lower rates on other forms of credit, among them?home mortgages. For a time, those moves seemed to revive growth: gross domestic product and hiring picked up last year, and the housing market appeared to have stabilized.

Despite a flurry of?press reports of possible new moves, the Fed is not expected to make any fresh announcements before its next two-day policy meeting next week. Even then, most of the measures under consideration have already been tried.

Buying more bonds could help prop up the financial markets, but would do little to spur borrowing and lending.?With interest rates at or near record lows, extending the promise to provide ultra-low rates beyond 2014, by itself, isn?t likely to encourage businesses and consumers to take on more risk.

So, with global economy slowing, the Fed is reaching deeper into its toolbox.

With borrowers on the sidelines, Fed policy makers are considering measures to try to prod bankers to push more money into the system. One such move would be to reward banks that make more loans, an idea borrowed from a recent program launched by the Bank of England. Bernanke hinted to reporters in June that the Fed was considering the plan.

Another measure aimed at prodding bankers to move more money out of their vaults and back into the economy would involve cutting the interest rate the Fed pays financial institutions to park their cash reserves with the central bank, which now stands at 0.25 percent.

But no matter how many creative new moves they try, Fed chairman Ben Bernanke has conceded that the impact of these policies will be limited. As he warned lawmakers last week, the central bank faces major obstacles to its mission of promoting strong growth and steady prices that are beyond its control.

"The recovery in the United States continues to be held back by a number of other headwinds, including still-tight borrowing conditions for some businesses and households, and the restraining effects of fiscal policy and fiscal uncertainty," Bernanke told a Senate panel.

Translation: Companies and consumers are still having a hard time qualifying for loans. And unless Congress and the White House head off the looming $600 billion ?fiscal cliff? of massive tax increases and spending cuts, there is little the central bank can do to stave off another recession.

The Fed isn?t alone in its?predicament.

With the world now locked in what appears to be a coordinated slowdown, central banks around the world have been flooding the system with money to prod businesses and consumers to borrow and spend.

But the global economy continues to lose momentum. The slowdown is most pronounced in Europe, where a deepening debt crisis is weighing on business and consumer confidence and hammering the banking system.

Like their American counterparts, European central bankers are struggling to push money into the economy.? But deep government spending cuts in Greece and Spain have left many households without a paycheck to spend.?And in the midst of a debt-induced a financial storm, business and consumers across the continent are in no mood to borrow. A closely watched European Central Bank survey Wednesday showed that demand for credit remains weak in the eurozone.

In China, the last major economy showing strong growth, that forward momentum is also slowing. Though still booming compared to developed economies, Chinese officials are trying to steer their emerging economy on a course that maintains robust growth but avoids a ruinous run-up in prices.

After adopting measures last year to cool an emerging price bubble, Beijing is now moving to boost growth again. But those measures are expected to be too limited to help revive the rest of the global economy. ?

Reuters contributed to this report.

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Discussing the state of the U.S. markets, and whether more Fed action is necessary, with CNBC contributors Joe Lavorgna and Ron Insana, and CNBC's Steve Liesman.

Source: http://economywatch.msnbc.msn.com/_news/2012/07/25/12950349-fed-has-few-options-as-global-growth-slows?lite

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